diff --git a/app/src/mouse_capture.c b/app/src/mouse_capture.c
index 1420bad6..ee96ae60 100644
--- a/app/src/mouse_capture.c
+++ b/app/src/mouse_capture.c
@@ -1,16 +1,19 @@
 #include "mouse_capture.h"
 
+#include "shortcut_mod.h"
 #include "util/log.h"
 
 void
-sc_mouse_capture_init(struct sc_mouse_capture *mc, SDL_Window *window) {
+sc_mouse_capture_init(struct sc_mouse_capture *mc, SDL_Window *window,
+                      uint8_t shortcut_mods) {
     mc->window = window;
+    mc->sdl_mouse_capture_keys = sc_shortcut_mods_to_sdl(shortcut_mods);
     mc->mouse_capture_key_pressed = SDLK_UNKNOWN;
 }
 
 static inline bool
-sc_mouse_capture_is_capture_key(SDL_Keycode key) {
-    return key == SDLK_LALT || key == SDLK_LGUI || key == SDLK_RGUI;
+sc_mouse_capture_is_capture_key(struct sc_mouse_capture *mc, SDL_Keycode key) {
+    return sc_shortcut_mods_is_shortcut_key(mc->sdl_mouse_capture_keys, key);
 }
 
 bool
@@ -25,7 +28,7 @@ sc_mouse_capture_handle_event(struct sc_mouse_capture *mc,
             break;
         case SDL_KEYDOWN: {
             SDL_Keycode key = event->key.keysym.sym;
-            if (sc_mouse_capture_is_capture_key(key)) {
+            if (sc_mouse_capture_is_capture_key(mc, key)) {
                 if (!mc->mouse_capture_key_pressed) {
                     mc->mouse_capture_key_pressed = key;
                 } else {
@@ -42,7 +45,7 @@ sc_mouse_capture_handle_event(struct sc_mouse_capture *mc,
             SDL_Keycode key = event->key.keysym.sym;
             SDL_Keycode cap = mc->mouse_capture_key_pressed;
             mc->mouse_capture_key_pressed = 0;
-            if (sc_mouse_capture_is_capture_key(key)) {
+            if (sc_mouse_capture_is_capture_key(mc, key)) {
                 if (key == cap) {
                     // A mouse capture key has been pressed then released:
                     // toggle the capture mouse mode
diff --git a/app/src/mouse_capture.h b/app/src/mouse_capture.h
index 53018c19..f352cc13 100644
--- a/app/src/mouse_capture.h
+++ b/app/src/mouse_capture.h
@@ -9,14 +9,17 @@
 
 struct sc_mouse_capture {
     SDL_Window *window;
+    uint16_t sdl_mouse_capture_keys;
 
     // To enable/disable mouse capture, a mouse capture key (LALT, LGUI or
     // RGUI) must be pressed. This variable tracks the pressed capture key.
     SDL_Keycode mouse_capture_key_pressed;
+
 };
 
 void
-sc_mouse_capture_init(struct sc_mouse_capture *mc, SDL_Window *window);
+sc_mouse_capture_init(struct sc_mouse_capture *mc, SDL_Window *window,
+                      uint8_t shortcut_mods);
 
 void
 sc_mouse_capture_set_active(struct sc_mouse_capture *mc, bool capture);
diff --git a/app/src/screen.c b/app/src/screen.c
index 146f10a5..1d694f12 100644
--- a/app/src/screen.c
+++ b/app/src/screen.c
@@ -445,7 +445,7 @@ sc_screen_init(struct sc_screen *screen,
     sc_input_manager_init(&screen->im, &im_params);
 
     // Initialize even if not used for simplicity
-    sc_mouse_capture_init(&screen->mc, screen->window);
+    sc_mouse_capture_init(&screen->mc, screen->window, params->shortcut_mods);
 
 #ifdef CONTINUOUS_RESIZING_WORKAROUND
     if (screen->video) {
diff --git a/app/src/usb/scrcpy_otg.c b/app/src/usb/scrcpy_otg.c
index 9595face..1a7e9544 100644
--- a/app/src/usb/scrcpy_otg.c
+++ b/app/src/usb/scrcpy_otg.c
@@ -185,6 +185,7 @@ scrcpy_otg(struct scrcpy_options *options) {
         .window_width = options->window_width,
         .window_height = options->window_height,
         .window_borderless = options->window_borderless,
+        .shortcut_mods = options->shortcut_mods,
     };
 
     ok = sc_screen_otg_init(&s->screen_otg, &params);
diff --git a/app/src/usb/screen_otg.c b/app/src/usb/screen_otg.c
index aabb8a7f..18377074 100644
--- a/app/src/usb/screen_otg.c
+++ b/app/src/usb/screen_otg.c
@@ -70,7 +70,7 @@ sc_screen_otg_init(struct sc_screen_otg *screen,
         LOGW("Could not load icon");
     }
 
-    sc_mouse_capture_init(&screen->mc, screen->window);
+    sc_mouse_capture_init(&screen->mc, screen->window, params->shortcut_mods);
 
     if (screen->mouse) {
         // Capture mouse on start
diff --git a/app/src/usb/screen_otg.h b/app/src/usb/screen_otg.h
index 850a6ae5..427723ad 100644
--- a/app/src/usb/screen_otg.h
+++ b/app/src/usb/screen_otg.h
@@ -35,6 +35,7 @@ struct sc_screen_otg_params {
     uint16_t window_width;
     uint16_t window_height;
     bool window_borderless;
+    uint8_t shortcut_mods; // OR of enum sc_shortcut_mod values
 };
 
 bool